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Community sources frame the 5-on/2-off and 8-week-cycle pattern around cost and letting IGF-1 normalize between blocks

Presented at the 38th annual meeting of the Obesity Society (TOS) held at ObesityWeek , November 26, 2020: Oral 084

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They interfere with testosterone production, impair sperm quality, and even disrupt hormone signaling in the brain (through the hypothalamic-pituitary-gonadal axis)

Self-reported data, especially from platforms like Reddit, can introduce bias, as it often captures a narrower or more vocal subset of users