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Beyond the EPR effect: Intravital microscopy analysis of nanoparticle drug delivery to tumors

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For a 75 to 90kg adult, that translates roughly to 190 to 900mcg daily, which brackets the 200 to 500mcg range being used in practice

3.3.6 Regulatory effects of TCMPs on genes and proteins in gut microbiota-associated pathways Among the nine included studies, we further summarized the pathways through which TCMPs exert therapeutic effects on RA and systematically cataloged the involved genes and proteins ( Table 3 )