mycotoxins deplete glutathione levels depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells Gallic acid antagonizes deoxynivalenol toxicity

Biol Trace Elem Res 201:29422954

Traditional oral glutathione is poorly absorbed (only ~10% reaches the bloodstream), while IV therapy is costly and temporary

Glutathione synthesis is also supported by hepatic cysteine production via the transsulfuration pathway, which converts methionine to cysteine through homocysteine intermediates (7-8)

Heart attacks and resulting cardiac damage are caused by heart disease

Participants included 57 children diagnosed with Autistic Spectrum Disorder (3-7 years old

Authors proposed a model wherein PL enters the cell, is hydrolyzed in its active form (hPL) with subsequent formation of a hPL:GSH complex that binds the active site of GSTP1-1 causing its inhibition (Fig