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Robert Kushner: I think both are correct

At the cellular level, B12 acts as a cofactor for two critical enzymatic reactions: Methionine synthase converts homocysteine to methionine, essential for DNA methylation and synthesis Methylmalonyl-CoA mutase involved in fatty acid metabolism and myelin production By restoring adequate B12 levels, injections enable normal red blood cell maturation in the bone marrow, correcting the megaloblastic anaemia

The lack of an antitumour effect from the loss of intracellular GSH suggested that extracellular GSH is instead crucial for tumour growth

Takeaway Owing to high antioxidant properties, Glutathione is a potent supplement

CagriSema may become an important Novo Nordisk follow-up platform if the amylin-plus-GLP-1 combination proves durable and tolerable

The best approach is to verify the patient's specific formulary before prescribing