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However, prolonged activation of AMPK by AICAR has been reported to trigger beta cell apoptosis 32,33

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Last reviewed: July 13, 2026 Last updated: July 13, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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