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The findings provide direct evidence that variation in the genes targeted by GLP-1 medications contribute to why people respond differently to GLP-1 therapies
The results follow previous research* from the same international team finding that weekly injections of semaglutide were linked to a 20% reduction in major adverse cardiac events (MACE) such as heart attacks and strokes for people with obesity or who were overweight and had cardiovascular disease
Arrange a routine appointment with your GP or diabetes nurse if: Injection site reactions persist beyond one week or worsen progressively You develop a mild rash that does not resolve within a few days Skin changes cause concern or uncertainty about continuing treatment You experience persistent itching without visible rash When consulting your healthcare provider, provide comprehensive information including when the skin changes began, their location and appearance, any associated symptoms, and whether you have started any other new medications or products
All of these medications are weekly injections except for Saxenda, which is a daily injection and Rybelsus, which is an oral form of semaglutide
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