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The frequency and intensity of surveillance should be individualized based on baseline cancer risk, duration of peptide therapy, and the presence of any concerning symptoms or clinical findings

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Several recent studies have shown that 4-PSQ reversed OXA-induced mechanical and thermal hypersensitivity, ameliorated chemotherapy-induced oxidative imbalance by reducing reactive species (RS) levels, normalizing glutathione peroxidase (GPx), catalase (CAT), superoxide dismutase (SOD) and acetylcholinesterase (AChE) activities in all tissues [161], and reversed aging-aggravated by reducing ROS and NOx levels [162]

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