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Symptom Monitoring: Even though serious adverse events did not occur in trials, individual monitoring for headache, gastrointestinal symptoms, or unusual effects allows for early detection of tolerability issues and appropriate management adjustments
In this study, all early and late phase markers of odonto/osteogenic differentiation were highly expressed in IGF-1-treated SCAPs with the low-expression of hsa-let-7c , but significantly downregulated in Let-7c overexpression group, indicating that hsa-let-7c was paramount to the IGF-1/IGF-1R/ hsa-let-7c axis
Selective is a pharmacological term of art describing receptor pathway specificity it is not a safety claim
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