Differential Item Functioning (DIF) analysis was done to determine measurement invariance between Asian versus White, Black versus White, English versus Spanish speaking, low versus higher income, married versus unmarried, those with private or public insurance, young versus older individuals, and single versus multiple parity participants
Yet, these side effects often diminish over time
One study examining patients who had undergone bariatric surgery and subsequently used semaglutide found mean vitamin b12 levels decreased from 567 to 494 mcg per deciliter over 12 months
Int J Pharm 599:120351 Chua L-M, Lim M-L, Chong P-R, Hu ZP, Cheung NS, Wong B-S (2012) Impaired neuronal insulin signaling precedes A 42 Accumulation in female APPsw/PS1E9 Mice
FDA-approved doesnt have to mean expensive
Furthermore, a prespecified analysis of the SELECT trial presented at the European Congress of Obesity 2024 revealed that the magnitude of this treatment effect with semaglutide was independent of the extent of achieved weight loss 32
