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Especially important with pre-existing conditions, long-term use, or GH peptides

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While human data is more limited, the clinical picture is consistent: semaglutide users who experience persistent GI issues often show lower microbiome diversity on stool testing than those who tolerate the medication well

The cost of Zepbound varies, but without insurance, it can be around $1,000 to $1,300 per month

Specifically, antagonizing NMDA receptors in the brainstem has been associated with an increase in short-term food intake 6,7

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