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Several large studies, including the SUSTAIN and LEADER trials, have followed patients for several years. Benefits of GLP-1 for weight loss and diabetes Unlike many other weight loss drugs that just focus on suppressing appetite or fat, GLP-1 medications not only help with weight loss but also address some of the underlying causes of obesity, like insulin resistance, said Galbraith

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A 2025 preformulation study published in the Journal of Peptide Science examined semaglutide stability across multiple temperature conditions