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(jofem.org) The best-case signal: modest weight loss in a shorter trial A frequently cited 12-week randomized trial result (as summarized in reviews) reported: ~2.6 kg average loss with AOD-9604 1 mg/day vs ~0.8 kg with placebo (PMC) This is the kind of result that can be statistically meaningful, clinically modest, and very sensitive to study design (diet, activity, baseline metabolic status, adherence)
Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study
15 mg Dose: Resulted in a staggering average of 20.9% body weight loss (amounting to roughly 52 lbs per participant on average)
But the real proof came from the head-to-head trial
Clean, fast delivery and my provider is genuinely responsive when I have questions." Derek, 43 "Down 22 lbs in 10 weeks
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