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The tirzepatide dose groups and regimens were as follows: 12 mg (4 mg for weeks 0-3, 8 mg for weeks 4-7, and 12 mg for weeks 8-11), 15 mg-1 (2.5 mg for weeks 0-1, 5 mg for weeks 2-3, 10 mg for weeks 4-7, and 15 mg for weeks 8-11), and 15 mg-2 (2.5 mg for weeks 0-3, 7.5 mg for weeks 4-7, and 15 mg for weeks 8-11)

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Previously, some studies have linked greater weight loss to better maintenance of weight loss, while others have linked it to more significant weight regain [38,39,40]

GLP-1R agonists ameliorate peripheral nerve dysfunction and inflammation via p38 MAPK/NF-B signaling pathways in streptozotocin-induced diabetic rats

MIC B12 shots add Methionine, Inositol, and Choline to the mix