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At year 1, nausea and/or vomiting was associated with greater weight loss with liraglutide 3.0 mg, but even those who did not experience these events lost more weight than those on placebo or orlistat

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Carol Fabian, who has been investigating the effects of the GLP-1 receptor agonist tirzepatide on blood, imaging, and breast tissue biomarkers in women with obesity and other risk factors for breast cancer

Tirzepatide (the generic name for the medication) is a gastric inhibitory polypeptide (GIP) and a glucagon-like peptide (GLP-1) receptor agonist

Gross necropsy and histopathologic examination found no organ damage in liver, spleen, lung, kidney, brain, thymus, prostate, ovaries, or gastric wall