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The potential success of this approach is enhanced given that GIP, GLP-1, and GLP-2 based drugs are already in clinical use, although postulated benefits on bone health still need to be fully confirmed ( Figure 3 )

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Innovation : The current AOM pipeline comprises 157 clinical-stage assets, including 7 in phase 3, and spans over 60 mechanisms of action, while 43% of all AOM assets are oral therapies (see Figure 2)

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Save Dihexa is an angiotensin-IV-derived oligopeptide marketed as a research nootropic, and its honest safety picture starts with an absence: there are no published human clinical trials of Dihexa, and therefore no human safety, toxicology, or pharmacokinetic data of any kind

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The lack of consensus on adult neurogenesis in non-human primates has had tremendous consequences for neuroscientists since it was considered as a prerequisite to validate its presence in humans

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If youre stuck if your medications are doing something but not enough, if your flares keep coming, if your fatigue wont lift theres a metabolic piece of your puzzle that probably hasnt been addressed yet

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