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However, it is important to note that erythrocytes generate ROS primarily as a result of (i) hemoglobin oxidation, which can be considered as an iron-mediated Fenton reaction, (ii) the activity of NAPDH oxidase and (iii) xanthine oxidoreductase, while in nucleated cells ROS are mainly generated in the mitochondrial electron transport chain
UpToDate: Accessed Jan
Advances in experimental medicine and biology , 1032 , 37-53
Although the peptide is reported to be stable in gastric juice, its bioavailability may be lower with this route
They have not been evaluated by the Food and Drug Administration, and are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety
In primary care, awareness of these background risks can be useful when assessing ambiguous non-pigmented lesions and should further lower the threshold for urgent referral in primary care
