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It is worth noting that research comparing GLP-1RAs with six anti-diabetes drugs revealed that there is no significant difference in lowering the risk of HCC between GLP-1RAs and metformin or DDP-4i (Wang et al., 2024)

The difference likely relates to the specific conformational changes each agonist induces in the receptor, which determines which G-protein pathways are preferentially activated

The majority of users source the drug via underground online vendors at costs ranging from A$30-50 for a one-month supply, and self-administer the injections at home

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