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Chloramphenicol, though rarely used in modern practice, can antagonize the hematologic response to vitamin B12 in patients with megaloblastic anemia
doi: 10.1371/journal.ppat.1009168 94 HoNIHuis In t VeldLGMvan Eck van der SluijsJHeutsBMHLoomanMWGKers-RebelEDet al
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This sublingual route of administration bypasses the digestive system, avoiding the first-pass metabolism in the liver, which can significantly reduce the bioavailability of certain medications when taken orally
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