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Most available evidence comes from laboratory and animal studies, where researchers have observed potential effects on: Tendon healing Ligament repair Muscle recovery Gastrointestinal tissue repair Angiogenesis Inflammatory signaling Although these findings are promising, robust human clinical trials remain limited

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Gene sets related to the MAPK and mTOR signaling pathways were retrieved from the Molecular Signatures Database (MSigDB) via the msigdbr R package

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Hepatology 70 , 711724 (2019)