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Add one high-fiber food at a time and give your body a week to adjust

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This tri-agonist mechanism distinguishes it from currently approved agents such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro), which act on one or two of these pathways respectively

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Furthermore, a prespecified subgroup analysis of HF individuals from the SELECT trial evaluating the effects of semaglutide on cardiovascular outcomes in people with overweight or obesity, which included 2,273 HFpEF and 1,347 HFrEF patients, showed that the therapy was associated with a reduction in the HF composite outcome (cardiovascular death or HF hospitalisation/emergency visit) across LVEF, suggesting that GLP-1 RAs may improve outcomes at least in obese HF patients regardless of diabetes status

& Levitt, P