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Research has identified specific gene variations that affect how individuals respond to these medications, influencing both appetite regulation and insulin sensitivity

10.1038/s41419-019-1753-4 68 HawkinsB

Others find that as their body adjusts to the medication, they need a higher dose to maintain the same appetite control

When they occur at a low dose, they actually tell us that the patient is sensitive to [the medication] and likely to lose weight on a low dose, said Professor Lean

Patients on immunosuppressants or blood thinners are also assessed carefully