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Cytosolic acetoacetate is converted to acetoacetyl-CoA which is then hydrolyzed into two moles of acetyl-CoA as described in the Nonoxidative Metabolic Fates of Ketones section below
(9) When combined, these peptides appear to exert a synergistic action on the pituitary gland, which might result in enhanced growth hormone production
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In non-diabetic individuals, this mechanism reduces appetite intensity and increases feelings of fullness without requiring blood sugar correction
Clinical studies in young (Lieberman et al