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Without a protein surplus, you're amplifying a signal your body can't act on

9,1216 Two trials (Harmony Outcomes [Albiglutide and Cardiovascular Outcomes in Patients With Type 2 Diabetes and Cardiovascular Disease] and AMPLITUDE-O) evaluated the effect of a GLP-1 receptor agonist on a primary outcome of major adverse cardiovascular events, and one trial (FLOW [Effect of Semaglutide Versus Placebo on the Progression of Renal Impairment in Subjects With Type 2 Diabetes and Chronic Kidney Disease]) evaluated the effect of a GLP-1 receptor agonist on a primary outcome of sustained 50% reduction in eGFR, kidney failure, or cardiovascular or kidney failurerelated death

2008 Aug;29(5):535-59

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Hepcidin dysregulation is also common in cancer cells: increased synthesis leads to negative regulation of ferroportin and iron export (358, 359)

Executive summary of the Th ird Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)