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Rather than relying on massive surplus to ensure adequate nutrients for muscle building, the improved insulin sensitivity and nutrient partitioning from Retatrutide may allow muscle growth from smaller surpluses that would normally be insufficient

Avoiding strenuous exercise immediately after eating may reduce abdominal discomfort

doi: 10.1016/j.biopsych.2015.02.020 72 HamonM.BlierP

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With repeated dosing, IGF-1 remains elevated above baseline for up to 28 days