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0.51 mL) into a fresh syringe and tap out air bubbles do not add any diluent

Lee and Padgett 2021 The study's limitations are genuine and must be stated: it is retrospective, uncontrolled, has no placebo arm, involves patients from a clinic with commercial interest in peptide therapy, and the sample size of 16 provides insufficient statistical power to draw definitive conclusions

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Non-randomized controlled trials and observational studies, including cohort and cross-sectional studies, were excluded from this study

Melatonin may potentiate this effect

Discussion and conclusions Drug desensitization is the sole treatment choice in the patients allergic to a drug which has no alternatives