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Semaglutide 2.4 mg long-term clinical outcomes in patients with obesity or overweight: a real-world retrospective cohort study in the United States (SCOPE 12 months)

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Although it does not directly interfere with the mechanism of action of tirzepatide, it reduces its efficacy through several indirect factors, such as increased calorie intake, reduced inhibition leading to overeating and poor food choices, slower fat metabolism, and a higher risk of hypoglycemia and gastrointestinal side effects

Phase 2 Trial Results The Phase 2 trials of Mazdutide have yielded impressive results, particularly in terms of weight loss efficacy