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Cell Cycle 11 , 22602267 (2012)

Modifying a drug delivery system with a brain targeting agent is one of the effective approaches to develop a brain targeting drug delivery system

Cellular senescence is characterized by a stable arrest in the cell cycle and encompasses a range of cellular changes that culminate in the development of a complex, pro-inflammatory secretory profile known as the senescence-associated secretory phenotype (SASP), which plays a critical role in fibrosis and tumors by affecting numerous processes, including invasion and therapy resistance 10

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There was also a significant difference compared with statin alone in change in HDL cholesterol