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INTRODUCTION Glutathione (GSH), the major intracellular thiol compound, is a ubiquitous tripeptide produced by most mammalian cells and it is the main mechanism of antioxidant defense against reactive oxygen species (ROS) and electrophiles

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To determine, firstly, whether mean metabolite component scores in patients with stable schizophrenia differ from mean scores in healthy controls, and secondly, whether this difference is significantly leveraged by the sub-group of patients with residual schizophrenia, we regressed each component score in turn on two participant variables using a hierarchical regression model