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Urz O, et al

The alpha-amino nitrogen of the glycine, the deprotonated amide nitrogen of the peptide bond between glycine and histidine, and an imidazole nitrogen of the histidine side chain form the primary coordination sphere

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This pushes the air into the vial and makes it easier to withdraw your prescribed amount of units

Study participants were given 20 grams as an oral supplement daily for three months