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The early effects of GSTO1 inhibition by C1-27 (4 h treatment) predominantly involved induction of several stress-response-associated genes ( OSGIN1 , HMOX1 , SLC7A11 , DNAJB9 and so on) (Supplementary Table 14)
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As we age, the synthesis of these proteins naturally declines, leading to wrinkles, sagging skin, and loss of resilience
TB-500 has been studied for wound healing and skin repair, cardiac tissue recovery, corneal repair, hair follicle stimulation, and inflammatory modulation
Hum Mol Genet (2014) 23:2439
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