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They increase oxidative stress, damage cellular structures, and promote the fibrotic changes associated with permanent hair loss

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Decrease of Cav-1 binding released the eNOS and subsequently enhanced the activation of eNOS

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In co-cultures, endothelial cells are grown on the basolateral side of the transwell inset on the membrane, while the other cell types are grown on the underside of the membrane or in the base of the cell culture dish