10.1038/onc.2015.20 34 GuiY.YeganehM.RamanathanS.LeblancC.PomerleauV.FerbeyreG.et al (2011)
Each dose escalation resets the timeline partially
The STEP 1 trial, for example, found that the average weight loss over 68 weeks was 14.9%
This includes patients with acute muscle strains, tendon irritation, ligament sprains, plantar fascia irritation, Achilles tendinopathy, patellar tendinopathy, rotator cuff irritation, tennis elbow, golfers elbow, or localized joint-adjacent soft-tissue pain
Second, GLP-1 affects the gut microbiome, intestinal permeability, and gut-derived inflammation, none of which require weight loss
Being able to walk into Walmart or CVS and purchase Replenza off the shelf is a convenience advantage that Willow and many other GLP-1 supplements do not offer