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The primary actions of GLP-1 include stimulating insulin secretion from pancreatic beta cells in response to elevated blood glucose (importantly, this insulin release is glucose-dependent, reducing hypoglycaemia risk), suppressing glucagon release (which prevents the liver from producing excess glucose), and slowing gastric emptying

Without insurance, brand-name GLP-1s, like Ozempic, Wegovy and Mounjaro, can run upward of $1,000 per month, and even with coverage, copays can be steep, he says

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Gene Activation : It up-regulates genes related to collagen synthesis (COL1A1, COL3A1) and elastin formation, making the skin look firmer and younger

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