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Curr Opin Immunol
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Discontinue use and speak with your provider if needed
vivo 24 (4), 401408
However, formulation studies often test several active ingredients together, making it difficult to attribute the result to one peptide.[2] A 2026 systematic review and meta-analysis of oral and topical peptides, covering 19 randomised controlled trials and 1,341 participants, found that peptides significantly improved skin hydration and brightness, with a modest pooled effect on wrinkle reduction (mean difference 0.27, p = 0.04)
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