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The absence of reported harm in rodents does not confirm human safety
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Animal research has confirmed the high oral bioavailability of 5-amino-1MQ, making it suitable for administration in capsule form [14]
In dietinduced obese mice, NNMTi treatment significantly reduced liver weight, liver volume, and hepatic triglyceride levels, alleviated hepatic steatosis and inflammatory infiltration, downregulated inflammatory factors (such as TNF and IL6) and lipogenic genes (such as FAS), and upregulated lipolytic genes (such as ATGL) in the liver
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