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A mitochondrial and metabolic substrate therefore represents a plausible upstream explanation for reduced interictal thalamic GSH

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1c) formed from the dietary methionine is transferred to Cys 4,5

Under the induction of oxidative stress, a part of HIF-1 is translocated to mitochondria, where it inhibits the respiratory chain by lowering the expression of mtDNA-encoded mRNA that responses to hypoxia, thus preventing the over-production of ROS and resisting oxidative stress

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In the present study, we investigated the effect of IGF-1 on the expression of cyclin D1, an important cell cycle regulatory protein, and a signaling pathway involved in IGF-1's effect on cyclinD1 expression in FRTL thyroid cells