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Abbreviations ADVANCE: action in diabetes and vascular disease AMI: acute myocardial infarction BID: twice daily bpm: beats per minute CI: confidence interval CVOT: cardiovascular outcome trial ELIXA: Evaluation of LIXisenatide in Acute coronary syndrome FIGHT: Functional Impact of GLP-1 for Heart Failure Treatment GLP-1 RA: glucagon-like peptide-1 receptor agonist HF: heart failure HR: heart rate LAR: long-acting release LEADER: Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results LIVE: Effect of LIraglutide on left VEntricular function in chronic heart failure patients with and without type 2 diabetes LS: least squares PK: pharmacokinetic QD: once daily QW: once weekly SE: standard error T2DM: type 2 diabetes mellitus References Inzucchi SE, Bergenstal RM, Buse JB, Diamant M, Ferrannini E, Nauck M, Peters AL, Tsapas A, Wender R, Matthews DR

Rodrigues VF, Elias-Oliveira J, Pereira S, et al

Then there's the problem of dosage and concentration

Notify your Provider of the use of blood-thinning medications and supplements such as aspirin, Coumadin, Plavix, fish oil, turmeric, ginger, cayenne peppers, vitamin E, garlic, ginkgo biloba, feverfew, grape seed extract, white willow, dong quai, aloe, meadowsweet, etc

Systemic absorption of intra-articular glucocorticoids has been widely described

Side Effect Profiles Gastrointestinal Side Effects Key Finding: CagriSema had highest overall GI event rate (79.6%)