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The reasoning: hormonal dysfunction in adipose tissue and hyperinsulinemia from insulin resistance can act similarly to reproductive hormones, directly contributing to the hyperandrogenism that defines PCOS

The primary endpoint (proportion achieving 5% additional weight loss) was met by 87.5% of the tirzepatide recipients versus 16.5% of the placebo recipients

This typically provides a more stable and prolonged effect compared to other methods like intravenous injection

Pain with coughing or sneezing typically reduces significantly

This helps people feel fuller longer and reduces spikes in blood sugar after meals

In other words, it may help a little, but not enough to replace proven prescription medications