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Leptin and adiponectin are two proteins that are usually imbalance in MASLD and this imbalance plays a role in the progression of hepatic steatosis and inflammation (187)
Switching to once-weekly insulin icodec versus once-daily insulin degludec in individuals with basal insulin-treated type 2 diabetes (ONWARDS 2): a phase 3a, randomised, open label, multicentre, treat-to-target trial
Stack results online are anecdotal
Side effects were mostly mild, and adherence and completion rates were high, which the team described as supporting feasibility in ordinary clinical settings