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doi: 10.1016/j.coi.2016.09.005 234 SenDRKaminskiJBarnitzRAKurachiMGerdemannUYatesKBet al

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The Pulsatile Release of "No DAC" The specific type of CJC-1295 used in the CJC-1295/Ipamorelin 5/5mg blend is the "No DAC" variant, and for good reason

A 2015 review in the Journal of Clinical Endocrinology confirming that GHRH analogs combined with ghrelin-pathway agonists produce a synergistic GH secretory response that exceeds additive effects when either compound is used alone provides the mechanistic basis for why combination therapy is the standard in supervised clinical settings