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In SV40-MES 13 cells, HMGB1 (high-mobility group box-1) has been recognized as a valuable factor of ferroptosis based on the Nrf2/HO-1 signaling pathway, proposing that HMGB1 is a new target for the treatment of DN [157]
10.1021/acscentsci.3c00414 ACS Cent
Changes in Glutathione System in Response to Exercise Training are Sex-Dependent in Humans
Moreover, the way GSH depletion can lead to immune system failure and make the end organs in danger of oxidative stress-mediated damage needs to be explained
2015 Oct;54(8):25112 Jones DP
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