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Participants were randomly assigned in a 2:1 ratio to receive once-weekly subcutaneous semaglutide 2.4 mg or placebo, alongside diet and physical activity counseling, for 52 weeks, followed by a 28-week off-treatment period

doi:10.1016/j.eclinm.2024.102475 Manne-Goehler J, Teufel F, Venter WDF

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Report persistent nausea, vomiting, or inability to maintain adequate nutrition or hydration

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