In OSF rats induced by betel nut extract administration through the buccal mucosa, EGCG hydrogel significantly reduces the expression of TGF-1 and type I collagen, with significant improvements in SOD and 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) clearance rate 145
Environ Health Perspect 116(1):2631
In a study of elderly individuals, those with the highest glutathione levels were found to be the healthiest
Figure 13 illustrates the effects of prenatal exposure to VPA, showing that HDAC inhibition may exacerbate oxidative stress by dysregulating the expression of genes involved in the antioxidant response, thereby promoting redox imbalance through increased ROS production and impaired antioxidant defenses (Gottlicher 2001
As a result, your body can better eliminate heavy metals, environmental pollutants and metabolic waste, supporting overall liver health and reducing fatigue
PMC 3243065