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There are several licensed GLP-1 medicines available in the UK, including semaglutide (sold under the brand names Wegovy, Ozempic, and Rybelsus), tirzepatide (Mounjaro), and liraglutide (sold under various brand names) [3]
The precise biological mechanism through which semaglutide potentially causes gastroparesis remains under investigation
THE GLP-1 LEGACY: A Behavioural Psychology Approach to Sustainable Weight Maintenance - Kindle edition by SHIRRAN, MARTIN AND MARION, Ogden, Professor Jane
Rosenstock, J., et al., Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial
Appl Physiol Nutr Metab (2010) 35(1):916
They simultaneously suppress somatostatin tone via hypothalamic interneurons, which amplifies the net GH pulse
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