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Semaglutide acts mainly at GLP-1 receptors, while tirzepatide acts at GIP and GLP-1 receptors
Statistical analysis was carried out using OriginPro 2021b (OriginLab Corporation), Microsoft Excel 2016 (Microsoft Corporation), and SPSS vers
Hepatology 50 , 20142021
Compared to peptide GLP- 1 receptor agonists, orforglipron, exhibits less receptor desensitization by increasing cyclic AMP signaling [105]
Enrichment map: a network-based method for gene-set enrichment visualization and interpretation
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