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In fact, around 400 BC in Greece, Hippocrates, often called the father of modern medicine, is said to have prescribed apple cider vinegar mixed with honey to treat a variety of illnesses

At this dose, your 100mg vial theoretically lasts 100 days

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This isn't because 1:1 is mechanistically optimal in some provable way it's because researchers studying combinations of these compounds chose 1:1 as the default and the literature accumulated around that choice

10.3390/biomedicines9070744 21 GojkovicS.KrezicI.VranesH.ZizekH.DrmicD.Batelja VuleticL.et al (2021b)

E., and Wing, D