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As an agonist at amylin and calcitonin receptors, cagrilintide is being investigated for its effect on appetite, food intake, and bodyweight, and it is engineered for a duration that supports once-weekly subcutaneous dosing
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Abbreviations ME: -mercaptoethanol BrdU: 5-bromo-2-deoxyuridine BSA: Bovine serum albumin DAB: 3,3-diaminobenzidine DMEM: Dulbeccos modified Eagles medium ECL: Enhanced chemiluminescence GSSSG: Glutathione trisulfide HGF: Hepatocyte growth factor HRP: Horseradish peroxidase HS: Horse serum mAb: Monoclonal antibody LASSS: Lipoic acid trisulfide SDS: Sodium dodecyl sulfate TTBS: Polyethylene sorbitan monolaurate (Tween20)-Tris-buffered saline Y: Tyrosine residue References Honda, S
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