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This effect was accompanied by a parallel accumulation of intracellular cAMP in ( B ) sAC +/+ caSMCs, but was lost in ( D ) sAC / caSMCs

Importantly, HER-2/neu overexpression is a clinically relevant target in human breast cancers, making this model highly translational for cancer risk mitigation in susceptible populations

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When an ischemic stroke occurs, the lack of blood and glucose leads to insufficient energy supply, causing the death of neurons in the infarcted brain area