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The nanosystem, with a size of approximately 90 nm, readily penetrated the stomata of rice leaves, where amidases and glutathione in the plant degraded the disulfide and amide bonds, triggering the sustained release of SA and bioavailable silicon within plant cells

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444 However, Hct may also rebound after bloodletting, and frequent use can lead to metabolic disorders, making it an impractical long-term treatment

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