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Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (which can be caused by ingestion of corrosives, extensive tumors, and conditions associated with gastric atrophy, such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy) Structural lesions leading to vitamin B 12 deficiency, including regional ileitis, ileal reactions, and malignancies Competition for vitamin B 12 by intestinal parasites or bacteria
T.Sells-MarchartS.Morante-CarrielJ
Oct2020;223(4):557.e1-557.e11
Free Radical Research , 31(4), 273300
Preventing Glutathione Depletion: Selenium eases the strain on glutathione